Martini, Aspierta Eels wrecks Landorus, they have a hard time getting past Tornadus EX and if they use something like Mewtwo to take it down, you'll have your own Mewtwos ready to go.
If you're going to play Ho-oh in that meta, make sure you run SSU and 3 Mewtwo. You really don't want to start Ho-oh against Keldeo and you're going to need to get it off the field if you do. Mewtwo singlehandedly takes down Blastoise/Keldeo, so just be wary of Shaymin (which you can obliterate with a Ho-oh at the end of the game) and you should be fine.
Also, the deck that they run seems very inconsistent, so you can beat them simply through consistency. How many supporters do you run?