Yes, but Mewtwo's biggest threat is Dusknoir. It can't stand spread at all, and Dusknoir's type is Mewtwo's weakness, where you can just use Dusknoir SF/Promo's attack to deal with an OHKO. Also, we may be seeing more Leafeon, Torterra, Empoleon, Rampardos, and other evolved Pokemon decks. So, Mewtwo should be used if your areas meta is basic Pokemon.