Just ignore them, they feed on reactions.
As someone who've had their last 14 months ruined because of this, I'll have to disagree.
People, and especially teens today are not interested in a particular reaction. Most of them decide to attempt to ruin other people's life just to boost their own self-esteem and ego. Sadly, I had to part with my group of friends when we were going to attend high school, because I didn't have good enough grades to attend the school they were applying for. I ended up having to attend the school I didn't plan to, with the people I desperately wanted to get away from. These people, despite having fantastic grades, are only interested in partying, working out and be around similarly attractive and perfect people, even the girls. There's no accept for any "weird" hobbys or interests, the people who are not like them will be treated awfully.
So there I am, in a classroom with the most popular, high-on-themselves people in my entire district. I tried to be open-minded and nice from our first hour together, but I was just... ignored. I am a completely average looking guy, and I practiced football (soccer) up until two years go. There was simply one fault with me; I was interested in video games and I didn't like partying. I was also burnt out from working out four times a week for the past ten years, and that was apparently catastrophic for my classmates. We just didn't have anything in common.
Whenever I tried to enter a conversation I was completely ignored. At the start the day they would greet everyone, except me. After school they would do social things together like going to the cinema, eating out and other neat stuff. They never invited me. A FaceBook group dedicated to the class was created at the start of the semester. Everyone was added, except me. All of my classmates worked in pairs when required to, I couldn't because no one were interested in working with me. These people are very focused on getting perfect grades, and compliment everyone when they score well on a test. When my English teacher announced that I was the only student who managed to get a perfect grade on our English exam, people got visibly upset. I felt like they wanted to kill me when the teacher left the classroom, and some students called their parents to arrange a meeting with the principal because I received a good grade, and they didn't. I overheard them mentioning that if the "dumb looser in their class" received a good grade, they should too. After things intensified I started skipping some classes, and eventually the entire day. At the end of the first semester I had been absent for sixty days, and I was in danger of being expelled.
After someoene told one of my classmates, who is one of the most popular and prettiest girls in the entire school that I'd been wanting to "date her for the past two years" it definitely made things harder (not true BTW). After one of my classmates wrote a post on her blog subtly based around me and the importance of "including everyone", I was deeply embarassed because people knew she talked about me. The fact that she didn't mean any of it, and only wanted to boost her own reputation was obvious. The final straw, however, came when the local paper published her post as front-page material on their website and in their paper version. I felt completely shattered.
To this day I haven't been able to attend school again. Our semester started two months ago, I haven't attended one class. Just today I was in a meeting with school officials and my mom because I was in danger of being expelled. I almost faint if I encounter my fellow peers. People laugh at me and give me mean stares when walking past me. My life is totally ruined. I'm having regular meetings with a psychologist because of my problems, and as of now I might not be able to finish high school before I'm 23-years old, literally. Sometimes I just want to end this. I barely get through it because I have good friends and an awesome mom.
Every day I think about where I would be now if I dared to seek help earlier. I don't know how your problem affects you, but believe me, it's better to seek help before it escalates any further. I'm fighting suicide thoughts, anxiety and depression daily, and I don't want anyone to go through this. Not seeking help earlier has led me to barely having a future. No matter the size of things, please don't be afraid of seeking help.