Here's what someone from another forums told me:
Player A (has 2 prizes and 1 card in deck):
Active Pokemon: [Machoke LM, weak: Psy] with 4 DREs, 4 Holon's Electrode, 4 Holon's Mags, 4 Holon's Castform, 4 Scramble Energy, and 35 basic energy attatched
Player B ( 2 cards in deck, 1 prize card):
Active: Dustox ex with [2] G Energy
Bench: Deoxys ex att. Forme (with 3 [P] energies), Gyarados d
Has Holon Research Tower in play
Turn x: player B attackes Machoke with silver wind
Turn x+1
layer A Draws his last card, its a basic energy... he attaches it, and ends
Turn x+2
layer B retreats Dustox and brings out Deoxys ex, attatches a strength charm, hits Machoke with his attack, choosing to discard 2 energy cards on Deoxys ex to do 50+ 20 x the amount of ENERGY on the defending Pokemon
Lets see...
Base + Double NRG + Triple NRG + Basic Energy + Strenth Charm Bonus + Gyarados d bonus x 2 for Weakness + 30 for Dustox ex bonus
(50 + ((16x2)x20) + ((4x3)x20) + (36x20) + 10 + 10) x 2 + 30
= (50 + (32x20)+(12x20)+(36x20)+10 +10)x2 +30
= (50 + (81x20) +20) x2 +30
= a grand total of 3450 damage if I calculated that right
very unlikely situation...thats the highest damage that I can think of lol
I think if theres a pokemon thats weak to psychic that could replace Machamp, and has an attack like Hariyama ex's (has to be a non-ex) second attack, and it attacked Dustox ex with it, the grand total would be 3470.
if you dont apply weakness, then the damage would be 1730
(Credit to Neo-Lionheart from croftminster)