Here's a tough one:
You are playing D&D (my favorite deck
), v.s Reshiram Typhlosion, the scenario is-
You have 2 Donphan out. 1 is active and 1 is on the Bench. Both have 1 Fighting Energy and both have no damage. With the Donphan on the bench is a Retreat Aid Dodrio with no Damage, a Zekrom with 30 damage and a DCE, a Reshiram with no damage no energy, and a Cleffa with 20 damage on it. You have 2 Prizes left.
In your hand is 1 Juniper, 1 Catcher, and 2 PlusPower. You know you have 1 Junk Arm and two Fighting Energy in your deck of 14 cards.
Your opponent has a Reshiram active with 60 damage and 3 Fire energy on it. A bench Reshiram with no damage, no energy. A Typhlosion with 60 damage on it and 1 Fire energy, and a Ninetails with no damage, no energy. They have two Fire energy in their discard pile. They have 2 Prizes left, and 5 unknown cards in their hand.
You have three choices. You can kill the Typhlosion with Earthquake using Catcher and the two PlusPowers and permanently cripple their field and hope to survive the next turn, KO-ing your Cleffa in the process. You can kill the Reshiram with Earthquake and automatically survive the next turn, but you have no way of immediatly taking the next prize, also KO-ing Cleffa in the process. You can also use the two PlusPower, Juniper, hope to hit one of the two Energy left in the deck, Retreat Donphan bringing up your Zekrom and killing the Reshiram. The problem with that is your opponent may or may not be able to kill you, because you don't know whats in their hand of 5 cards If they manage to kill your Zekrom, you automatically kill your Cleffa because Donphan is the only attacker you have left. But you do know that they have used 2 Junk Arms, 3 Catchers, and 2 PlusPower. Their deck has 16 Cards left in it.
I personally would kill Reshiram and hope that they do something stupid, or have some ingenious brain-child and pull off the victory. Hope you like this!
EDIT: If you come up with a better plan than I could under the circumstances, feel free to say it.