RE: Hardest video game?
Bowser's Inside Story is easy, just saying. Except for the Gauntlet, but that's just 1 tiny portion of a while game.
If I wanted to think of genuinely hard games...well, I haven't played very many, but there are a few that come to mind.
~Partners in Time. It's definitely the hardest of the Mario RPG series (that I've played) and requires you think ahead a little bit. The lack of MP in the game makes things a little bit trickier, instead you must buy items to use your specials. That, and bosses are usually quite difficult and lengthy. It wasn't really super-hard at any one point, just moderately hard throughout.
~Final Fantasy IV. Moderately hard throughout, PLUS really hard points in other places. Lunar Ruins was a pain to beat, and so was the plot. I wasn't used to my party characters randomly being dropped and added with little prior notice, so it took a while to get used to. I didn't really catch a break until I got to the last dungeon. Didn't like the game very much, but overall it was nice and challenging.
~YGO: The Sacred Cards. Dang, I hated this game. The deckbuilding rules were really irritating and usually you'd only have room for 1, maybe 2 heavy hitters in your deck due to the point scaling. And the point scaling was CRAZY. It ended up making duels mostly luck-based and hope that you'll draw the 1 card that will take care of all monsters your opponent can throw at you. The boss in the quarterfinals, and later the final boss, were without a doubt the hardest bosses I've ever had to face - especially the final, because of the GIGANTIC difficult jump. I heard Reshef of Destruction is even worse.
~Golden Sun: The Lost Age. Mostly because the whole game was a gigantic dungeon-crawler and that's all you seem to do for the whole game. For anyone who has played it, you will know that Air's Rock is one of the most hellish dungeons ever devised. The bosses aren't the hard part (not counting the superbosses) - the finding your way through the dungeons is. And the last extra boss of this game, Dullahan, is one boss that will send you home crying if you don't plan well in advance - he has a move that he does about once every 8 rounds that will basically reset the class setup of your entire front row (it about halves all their stats and strips them of many strong spells), meaning you'll have to wait for the classes to steadily recover again.
~Fire Emblem and/or Advance Wars. Made by the same people, same basic strategy. It's a strategy turn-based RPG - you have some units, the enemy has some units, and your goal is to defeat all enemies/seize a certain point/last for X turns/win within X turns, with the goal varying every level. Sounds simple, but it's quite complex. Intelligent Systems really knows how to design games.